BIOL 223 - Advanced Cell Biology
Semester Hours: 4
Periodically
Once thought to be the purview only of cell and molecular biologists, molecular and cellular methods are now commonly used to solve problems in all sub-disciplines of biology, including conservation, ecology and physiology. Discussion and application of the methods used during the study of membrane trafficking and cell signaling in human cell culture. Topics include CRISPR-Cas9 genome editing, RNA interference, protein structure and function, mechanisms of protein regulation, protein trafficking and expression, and cell signaling. This course provides training in industry-applicable techniques like ELISA (enzyme-linked substrate immunosorbence assay) and confocal immunofluorescence microscopy. Students will design independent experimental projects while developing scientific writing and presentation skills. Extensive critical reading of primary literature is required. (1 hour lecture, 5 hours lab.)
Prerequisite(s)/Course Notes:
An undergraduate course in cell biology or biochemistry is strongly recommended. Students will be expected to work in teams and complete some experimental protocols outside of regularly scheduled class sessions. Lab fee additional. No credit for BIO 223 if BIOL 167 is on the undergraduate transcript. (Formerly, BIO 238)
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